Folker Meyer is a Professor at the Department of Medicine and at the Computer Science Department of University of Duisburg-Essen.
The data science lab is part of the Institute for AI in medicine (IKIM), University Hospital Essen, Medical Faculty University of Duisburg-Essen. We are focused on efficient, reproducible and sustainable Data Science and Microbiome Analysis.
Data science brings together a number of disciplines and methods for the purpose of extracting knowledge from structured and unstructured data. It strives to achieve semantic integration of data from a variety of sources and disciplines, suitable technical platforms for integration are required to facilitate the process. Related to other disciplines like big data and machine learning, data science is part of the value-add chain from data to information to clinical and public health decision making.
Important aspects of data integration are suitable data exchange standards and data privacy, it is impossible to practice data science without good privacy and security concepts. The group aims for honor the principles of Data FAIRness as well as reproducible science via the use of workflow technology.
Microbiome and virome analysis presents an opportunity to assist with the rapid molecular characterization of infectious disease via DNA sequencing, It can also advance the early detection of life-threatening diseases e.g. sepsis, NEC, dysbiosis in patients with bone marrow transplants. Combined with a data science approach microbiome and virome analysis can provide vital clues for e.g. the detection of hospital borne infection, emergence of bacterial strains resistant to antibiotics and last but not least allow the establishment DNA base surveillance mechanism for the rapid and early detection of emerging DNA and RNA pathogens.
The group hosts the junior group MicrobiomeSepsisPred funded by the BMBF.
Wastewater based epidemiology (WBE) presents a unique opportunity to characterize the virome and microbiome of an entire community. WBE is a specialized form of environmental genomics and allows characterizing microbial and viral life in urban environments, integrating material from thousands of individuals. Using WBE we create preditive models of pathogens in the population and the environment. We also work towards the establishment of anomaly detection systems. The group routinely analyses samples from waste water treatments plants, the sewer system and the hospital environment.
Girardethaus Girardetstr. 8 House 8, 2nd floor 45131 Essen
Prof. Dr. Folker Meyer Office
@article{SCHMIEGE2023165458, title = {Analyzing community wastewater in sub-sewersheds for the small-scale detection of SARS-CoV-2 variants in a German metropolitan area}, journal = {Science of The Total Environment}, volume = {898}, pages = {165458}, year = {2023}, issn = {0048-9697}, doi = {https://doi.org/10.1016/j.scitotenv.2023.165458}, url = {https://www.sciencedirect.com/science/article/pii/S0048969723040810}, author = {Schmiege, Dennis and Kraiselburd, Ivana and Haselhoff, Timo and Thomas, Alexander and Doerr, Adrian and Gosch, Jule and Schoth, Jens and Teichgräber, Burkhard and Moebus, Susanne and Meyer, Folker}, keywords = {COVID-19, Public health, Small-scale, Single nucleotide variants (SNVs), Wastewater surveillance, Whole genome sequencing} }
@article{10.3389/fimmu.2023.1150667, author = {Bormann, Maren and Brochhagen, Leonie and Alt, Mira and Otte, Mona and Thümmler, Laura and van de Sand, Lukas and Kraiselburd, Ivana and Thomas, Alexander and Gosch, Jule and Braß, Peer and Ciesek, Sandra and Widera, Marek and Dolff, Sebastian and Dittmer, Ulf and Witzke, Oliver and Meyer, Folker and Lindemann, Monika and Schönfeld, Andreas and Rohn, Hana and Krawczyk, Adalbert}, title = {Immune responses in COVID-19 patients during breakthrough infection with SARS-CoV-2 variants Delta, Omicron-BA.1 and Omicron-BA.5}, journal = {Frontiers in Immunology}, volume = {14}, year = {2023}, url = {https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150667}, doi = {10.3389/fimmu.2023.1150667}, issn = {1664-3224} }
@article{10.3389/fmicb.2023.1267270, author = {Hartmann, Martin and Herzog, Claude and Brunner, Ivano and Stierli, Beat and Meyer, Folker and Buchmann, Nina and Frey, Beat}, title = {Long-term mitigation of drought changes the functional potential and life-strategies of the forest soil microbiome involved in organic matter decomposition}, journal = {Frontiers in Microbiology}, volume = {14}, year = {2023}, url = {https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1267270}, doi = {10.3389/fmicb.2023.1267270}, issn = {1664-302X} }
@article{https://doi.org/10.1002/mbo3.1347, author = {Stach, Tom L. and Sieber, Guido and Shah, Manan and Simon, Sophie A. and Soares, André and Bornemann, Till L. V. and Plewka, Julia and Künkel, Julian and Becker, Christian and Meyer, Folker and Boenigk, Jens and Probst, Alexander J.}, title = {Temporal disturbance of a model stream ecosystem by high microbial diversity from treated wastewater}, journal = {MicrobiologyOpen}, volume = {12}, number = {2}, pages = {e1347}, keywords = {ARG, freshwater, mesocosm, metagenomics, microbiome, stressor}, doi = {https://doi.org/10.1002/mbo3.1347}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/mbo3.1347}, eprint = {https://onlinelibrary.wiley.com/doi/pdf/10.1002/mbo3.1347}, year = {2023} }
@article{imangaliyevDiagnosisInflammatoryBowel2022, title = {Diagnosis of {{Inflammatory Bowel Disease}} and {{Colorectal Cancer}} through {{Multi-View Stacked Generalization Applied}} on {{Gut Microbiome Data}}}, author = {Imangaliyev, Sultan and Schl{\"o}tterer, J{\"o}rg and Meyer, Folker and Seifert, Christin}, year = {2022}, month = oct, journal = {Diagnostics}, volume = {12}, number = {10}, pages = {2514}, issn = {2075-4418}, doi = {10.3390/diagnostics12102514}, langid = {english} }
folker.meyer@uni-due.de Phone: +4920172377802
ivana.kraiselburd@uni-due.de Interests: Bacterial Diversity, Sepsis, and Machine learning & Prediction
kerstin.bornemann@uk-essen.de Phone: +492017237883
ricarda.schmithausen@uni-due.de
simon.magin@uk-essen.de
katharina.block@uk-essen.de
adrian.doerr@uk-essen.de
alexander.thomas@uk-essen.de
josefa.welling@uk-essen.de Interests: antibiotic resistances and ML
Ann-Kathrin.Brueggemann@uk-essen.de Interests: Time Series Data and 16s rDNA
jule.gosch@uk-essen.de
ryan.aydelott@uk-essen.de