Applied Computational Cancer Research - see all...

2024

J. Pozniak, D. Pedri, E. Landeloos, Y. Van Herck, A. Antoranz, L. Vanwynsberghe, A. Nowosad, N. Roda, S. Makhzami, G. Bervoets, L. F. Maciel, C. A. Pulido-Vicuna, L. Pollaris, R. Seurinck, F. Zhao, K. Flem-Karlsen, W. Damsky, L. Chen, D. Karagianni, S. Cinque, S. Kint, K. Vandereyken, B. Rombaut, T. Voet, F. Vernaillen, W. Annaert, D. Lambrechts, V. Boecxstaens, Y. Saeys, J. van den Oord, F. Bosisio, P. Karras, A. H. Shain, M. Bosenberg, E. Leucci, A. Paschen, F. Rambow, O. Bechter, and J. C. Marine. A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma. Cell. 2024. [doi] [url]

BibTeX

@article{RN194,
  author = {Pozniak, J. and Pedri, D. and Landeloos, E. and Van Herck, Y. and Antoranz, A. and Vanwynsberghe, L. and Nowosad, A. and Roda, N. and Makhzami, S. and Bervoets, G. and Maciel, L. F. and Pulido-Vicuna, C. A. and Pollaris, L. and Seurinck, R. and Zhao, F. and Flem-Karlsen, K. and Damsky, W. and Chen, L. and Karagianni, D. and Cinque, S. and Kint, S. and Vandereyken, K. and Rombaut, B. and Voet, T. and Vernaillen, F. and Annaert, W. and Lambrechts, D. and Boecxstaens, V. and Saeys, Y. and van den Oord, J. and Bosisio, F. and Karras, P. and Shain, A. H. and Bosenberg, M. and Leucci, E. and Paschen, A. and Rambow, F. and Bechter, O. and Marine, J. C.},
  title = {A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma},
  journal = {Cell},
  volume = {187},
  number = {1},
  pages = {166-183 e25},
  issn = {1097-4172 (Electronic)
  0092-8674 (Linking)},
  doi = {10.1016/j.cell.2023.11.037},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/38181739},
  year = {2024},
  type = {Journal Article}
}

2023

R. Varaljai, L. Zimmer, Y. Al-Matary, P. Kaptein, L. J. Albrecht, B. Shannan, J. C. Brase, D. Gusenleitner, T. Amaral, N. Wyss, J. Utikal, L. Flatz, F. Rambow, H. C. Reinhardt, J. Dick, D. R. Engel, S. Horn, S. Ugurel, W. Sondermann, E. Livingstone, A. Sucker, A. Paschen, F. Zhao, J. M. Placke, J. M. Klose, W. P. Fendler, D. S. Thommen, I. Helfrich, D. Schadendorf, and A. Roesch. Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma. Nat Cancer. 2023. [doi] [url]

BibTeX

@article{RN195,
  author = {Varaljai, R. and Zimmer, L. and Al-Matary, Y. and Kaptein, P. and Albrecht, L. J. and Shannan, B. and Brase, J. C. and Gusenleitner, D. and Amaral, T. and Wyss, N. and Utikal, J. and Flatz, L. and Rambow, F. and Reinhardt, H. C. and Dick, J. and Engel, D. R. and Horn, S. and Ugurel, S. and Sondermann, W. and Livingstone, E. and Sucker, A. and Paschen, A. and Zhao, F. and Placke, J. M. and Klose, J. M. and Fendler, W. P. and Thommen, D. S. and Helfrich, I. and Schadendorf, D. and Roesch, A.},
  title = {Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma},
  journal = {Nat Cancer},
  volume = {4},
  number = {9},
  pages = {1292-1308},
  issn = {2662-1347 (Electronic)
  2662-1347 (Linking)},
  doi = {10.1038/s43018-023-00610-2},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/37525015},
  year = {2023},
  type = {Journal Article}
}

B. Kruse, A. C. Buzzai, N. Shridhar, A. D. Braun, S. Gellert, K. Knauth, J. Pozniak, J. Peters, P. Dittmann, M. Mengoni, T. C. van der Sluis, S. Hohn, A. Antoranz, A. Krone, Y. Fu, D. Yu, M. Essand, R. Geffers, D. Mougiakakos, S. Kahlfuss, H. Kashkar, E. Gaffal, F. M. Bosisio, O. Bechter, F. Rambow, J. C. Marine, W. Kastenmuller, A. J. Muller, and T. Tuting. CD4(+) T cell-induced inflammatory cell death controls immune-evasive tumours. Nature. 2023. [doi] [url]

BibTeX

@article{RN61,
  author = {Kruse, B. and Buzzai, A. C. and Shridhar, N. and Braun, A. D. and Gellert, S. and Knauth, K. and Pozniak, J. and Peters, J. and Dittmann, P. and Mengoni, M. and van der Sluis, T. C. and Hohn, S. and Antoranz, A. and Krone, A. and Fu, Y. and Yu, D. and Essand, M. and Geffers, R. and Mougiakakos, D. and Kahlfuss, S. and Kashkar, H. and Gaffal, E. and Bosisio, F. M. and Bechter, O. and Rambow, F. and Marine, J. C. and Kastenmuller, W. and Muller, A. J. and Tuting, T.},
  title = {CD4(+) T cell-induced inflammatory cell death controls immune-evasive tumours},
  journal = {Nature},
  issn = {1476-4687 (Electronic)
  0028-0836 (Linking)},
  doi = {10.1038/s41586-023-06199-x},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/37316667},
  year = {2023},
  type = {Journal Article}
}

A. Talebi, V. de Laat, X. Spotbeen, J. Dehairs, F. Rambow, A. Rogiers, F. Vanderhoydonc, L. Rizotto, M. Planque, G. Doglioni, S. Motamedi, D. Nittner, T. Roskams, P. Agostinis, O. Bechter, V. Boecxstaens, M. Garmyn, M. O’Farrell, A. Wagman, G. Kemble, E. Leucci, S. M. Fendt, J. C. Marine, and J. V. Swinnen. Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy. J Exp Clin Cancer Res. 2023. [doi] [url]

BibTeX

@article{RN62,
  author = {Talebi, A. and de Laat, V. and Spotbeen, X. and Dehairs, J. and Rambow, F. and Rogiers, A. and Vanderhoydonc, F. and Rizotto, L. and Planque, M. and Doglioni, G. and Motamedi, S. and Nittner, D. and Roskams, T. and Agostinis, P. and Bechter, O. and Boecxstaens, V. and Garmyn, M. and O'Farrell, M. and Wagman, A. and Kemble, G. and Leucci, E. and Fendt, S. M. and Marine, J. C. and Swinnen, J. V.},
  title = {Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy},
  journal = {J Exp Clin Cancer Res},
  volume = {42},
  number = {1},
  pages = {92},
  issn = {1756-9966 (Electronic)
  0392-9078 (Print)
  0392-9078 (Linking)},
  doi = {10.1186/s13046-023-02664-7},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/37072838},
  year = {2023},
  type = {Journal Article}
}

L. Martins Nascentes Melo, D. Herrera-Rios, D. Hinze, S. Loffek, I. Oezel, R. Turiello, J. Klein, S. Leonardelli, I. V. Westedt, Y. Al-Matary, S. Egea-Rodriguez, A. Brenzel, M. Bau, A. Sucker, E. Hadaschik, F. Wirsdorfer, H. Hanenberg, N. Uhlenbrock, D. Rauh, J. Pozniak, F. Rambow, J. C. Marine, M. Effern, N. Glodde, D. Schadendorf, J. Jablonska, M. Holzel, and I. Helfrich. Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma. J Immunother Cancer. 2023. [doi] [url]

BibTeX

@article{RN63,
  author = {Martins Nascentes Melo, L. and Herrera-Rios, D. and Hinze, D. and Loffek, S. and Oezel, I. and Turiello, R. and Klein, J. and Leonardelli, S. and Westedt, I. V. and Al-Matary, Y. and Egea-Rodriguez, S. and Brenzel, A. and Bau, M. and Sucker, A. and Hadaschik, E. and Wirsdorfer, F. and Hanenberg, H. and Uhlenbrock, N. and Rauh, D. and Pozniak, J. and Rambow, F. and Marine, J. C. and Effern, M. and Glodde, N. and Schadendorf, D. and Jablonska, J. and Holzel, M. and Helfrich, I.},
  title = {Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma},
  journal = {J Immunother Cancer},
  volume = {11},
  number = {4},
  issn = {2051-1426 (Electronic)
  2051-1426 (Linking)},
  doi = {10.1136/jitc-2021-004150},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/37028818},
  year = {2023},
  type = {Journal Article}
}

K. F. Shoji, E. Bayet, S. Leverrier-Penna, D. Le Devedec, A. Mallavialle, S. Marionneau-Lambot, F. Rambow, R. Perret, A. Joussaume, R. Viel, A. Fautrel, A. Khammari, B. Constantin, S. Tartare-Deckert, and A. Penna. The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential. EMBO Rep. 2023. [doi] [url]

BibTeX

@article{RN64,
  author = {Shoji, K. F. and Bayet, E. and Leverrier-Penna, S. and Le Devedec, D. and Mallavialle, A. and Marionneau-Lambot, S. and Rambow, F. and Perret, R. and Joussaume, A. and Viel, R. and Fautrel, A. and Khammari, A. and Constantin, B. and Tartare-Deckert, S. and Penna, A.},
  title = {The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential},
  journal = {EMBO Rep},
  volume = {24},
  number = {4},
  pages = {e55069},
  issn = {1469-3178 (Electronic)
  1469-221X (Print)
  1469-221X (Linking)},
  doi = {10.15252/embr.202255069},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/36744297},
  year = {2023},
  type = {Journal Article}
}

Y. Hua, G. Vella, F. Rambow, E. Allen, A. A. Martinez, M. Duhamel, A. Takeda, S. Jalkanen, S. Junius, A. Smeets, D. Nittner, S. Dimmeler, T. Hehlgans, A. Liston, F. M. Bosisio, G. Floris, D. Laoui, M. Hollmen, D. Lambrechts, P. Merchiers, J. C. Marine, S. Schlenner, and G. Bergers. Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1(+) T lymphocyte niches through a feed-forward loop. Cancer Cell. 2023. [doi] [url]

BibTeX

@article{RN65,
  author = {Hua, Y. and Vella, G. and Rambow, F. and Allen, E. and Martinez, A. A. and Duhamel, M. and Takeda, A. and Jalkanen, S. and Junius, S. and Smeets, A. and Nittner, D. and Dimmeler, S. and Hehlgans, T. and Liston, A. and Bosisio, F. M. and Floris, G. and Laoui, D. and Hollmen, M. and Lambrechts, D. and Merchiers, P. and Marine, J. C. and Schlenner, S. and Bergers, G.},
  title = {Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1(+) T lymphocyte niches through a feed-forward loop},
  journal = {Cancer Cell},
  volume = {41},
  number = {1},
  pages = {226},
  issn = {1878-3686 (Electronic)
  1535-6108 (Linking)},
  doi = {10.1016/j.ccell.2022.12.006},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/36626867},
  year = {2023},
  type = {Journal Article}
}

2022

Y. Hua, G. Vella, F. Rambow, E. Allen, A. Antoranz Martinez, M. Duhamel, A. Takeda, S. Jalkanen, S. Junius, A. Smeets, D. Nittner, S. Dimmeler, T. Hehlgans, A. Liston, F. M. Bosisio, G. Floris, D. Laoui, M. Hollmen, D. Lambrechts, P. Merchiers, J. C. Marine, S. Schlenner, and G. Bergers. Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1(+) T lymphocyte niches through a feed-forward loop. Cancer Cell. 2022. [doi] [url]

BibTeX

@article{RN66,
  author = {Hua, Y. and Vella, G. and Rambow, F. and Allen, E. and Antoranz Martinez, A. and Duhamel, M. and Takeda, A. and Jalkanen, S. and Junius, S. and Smeets, A. and Nittner, D. and Dimmeler, S. and Hehlgans, T. and Liston, A. and Bosisio, F. M. and Floris, G. and Laoui, D. and Hollmen, M. and Lambrechts, D. and Merchiers, P. and Marine, J. C. and Schlenner, S. and Bergers, G.},
  title = {Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1(+) T lymphocyte niches through a feed-forward loop},
  journal = {Cancer Cell},
  volume = {40},
  number = {12},
  pages = {1600-1618 e10},
  issn = {1878-3686 (Electronic)
  1535-6108 (Print)
  1535-6108 (Linking)},
  doi = {10.1016/j.ccell.2022.11.002},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/36423635},
  year = {2022},
  type = {Journal Article}
}

P. Karras, I. Bordeu, J. Pozniak, A. Nowosad, C. Pazzi, N. Van Raemdonck, E. Landeloos, Y. Van Herck, D. Pedri, G. Bervoets, S. Makhzami, J. H. Khoo, B. Pavie, J. Lamote, O. Marin-Bejar, M. Dewaele, H. Liang, X. Zhang, Y. Hua, J. Wouters, R. Browaeys, G. Bergers, Y. Saeys, F. Bosisio, J. van den Oord, D. Lambrechts, A. K. Rustgi, O. Bechter, C. Blanpain, B. D. Simons, F. Rambow, and J. C. Marine. Author Correction: A cellular hierarchy in melanoma uncouples growth and metastasis. Nature. 2022. [doi] [url]

BibTeX

@article{RN67,
  author = {Karras, P. and Bordeu, I. and Pozniak, J. and Nowosad, A. and Pazzi, C. and Van Raemdonck, N. and Landeloos, E. and Van Herck, Y. and Pedri, D. and Bervoets, G. and Makhzami, S. and Khoo, J. H. and Pavie, B. and Lamote, J. and Marin-Bejar, O. and Dewaele, M. and Liang, H. and Zhang, X. and Hua, Y. and Wouters, J. and Browaeys, R. and Bergers, G. and Saeys, Y. and Bosisio, F. and van den Oord, J. and Lambrechts, D. and Rustgi, A. K. and Bechter, O. and Blanpain, C. and Simons, B. D. and Rambow, F. and Marine, J. C.},
  title = {Author Correction: A cellular hierarchy in melanoma uncouples growth and metastasis},
  journal = {Nature},
  volume = {611},
  number = {7934},
  pages = {E4},
  issn = {1476-4687 (Electronic)
  0028-0836 (Linking)},
  doi = {10.1038/s41586-022-05415-4},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/36261534},
  year = {2022},
  type = {Journal Article}
}

P. Karras, I. Bordeu, J. Pozniak, A. Nowosad, C. Pazzi, N. Van Raemdonck, E. Landeloos, Y. Van Herck, D. Pedri, G. Bervoets, S. Makhzami, J. H. Khoo, B. Pavie, J. Lamote, O. Marin-Bejar, M. Dewaele, H. Liang, X. Zhang, Y. Hua, J. Wouters, R. Browaeys, G. Bergers, Y. Saeys, F. Bosisio, J. van den Oord, D. Lambrechts, A. K. Rustgi, O. Bechter, C. Blanpain, B. D. Simons, F. Rambow, and J. C. Marine. A cellular hierarchy in melanoma uncouples growth and metastasis. Nature. 2022. [doi] [url]

BibTeX

@article{RN99,
  author = {Karras, P. and Bordeu, I. and Pozniak, J. and Nowosad, A. and Pazzi, C. and Van Raemdonck, N. and Landeloos, E. and Van Herck, Y. and Pedri, D. and Bervoets, G. and Makhzami, S. and Khoo, J. H. and Pavie, B. and Lamote, J. and Marin-Bejar, O. and Dewaele, M. and Liang, H. and Zhang, X. and Hua, Y. and Wouters, J. and Browaeys, R. and Bergers, G. and Saeys, Y. and Bosisio, F. and van den Oord, J. and Lambrechts, D. and Rustgi, A. K. and Bechter, O. and Blanpain, C. and Simons, B. D. and Rambow, F. and Marine, J. C.},
  title = {A cellular hierarchy in melanoma uncouples growth and metastasis},
  journal = {Nature},
  volume = {610},
  number = {7930},
  pages = {190-198},
  issn = {1476-4687 (Electronic)
  	0028-0836 (Linking)},
  doi = {10.1038/s41586-022-05242-7},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/36131018},
  year = {2022},
  type = {Journal Article}
}

Joanna Pozniak, Dennis Pedri, Ewout Landeloos, Yannick Van Herck, Asier Antoranz, Panagiotis Karras, Ada Nowosad, Samira Makhzami, Greet Bervoets, Michael Dewaele, Lukas Vanwynsberghe, Sonia Cinque, Sam Kint, Katy Vandereyken, Thierry Voet, Frank Vernaillen, Wim Annaert, Diether Lambrechts, Veerle Boecxstaens, Joost van den Oord, Francesca Bosisio, Eleonora Leucci, Florian Rambow, Oliver Bechter, and Jean-Christophe Marine. A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma. bioRxiv. 2022. Cold Spring Harbor Laboratory. [doi] [url]

BibTeX

@article{Pozniak2022.08.11.502598,
  author = {Pozniak, Joanna and Pedri, Dennis and Landeloos, Ewout and Herck, Yannick Van and Antoranz, Asier and Karras, Panagiotis and Nowosad, Ada and Makhzami, Samira and Bervoets, Greet and Dewaele, Michael and Vanwynsberghe, Lukas and Cinque, Sonia and Kint, Sam and Vandereyken, Katy and Voet, Thierry and Vernaillen, Frank and Annaert, Wim and Lambrechts, Diether and Boecxstaens, Veerle and van den Oord, Joost and Bosisio, Francesca and Leucci, Eleonora and Rambow, Florian and Bechter, Oliver and Marine, Jean-Christophe},
  title = {A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma},
  elocation-id = {2022.08.11.502598},
  year = {2022},
  doi = {10.1101/2022.08.11.502598},
  publisher = {Cold Spring Harbor Laboratory},
  url = {https://www.biorxiv.org/content/early/2022/08/13/2022.08.11.502598},
  eprint = {https://www.biorxiv.org/content/early/2022/08/13/2022.08.11.502598.full.pdf},
  journal = {bioRxiv}
}

II Verginadis, H. Avgousti, J. Monslow, G. Skoufos, F. Chinga, K. Kim, N. M. Leli, I. V. Karagounis, B. I. Bell, A. Velalopoulou, C. S. Salinas, V. S. Wu, Y. Li, J. Ye, D. A. Scott, A. L. Osterman, A. Sengupta, A. Weljie, M. Huang, D. Zhang, Y. Fan, E. Radaelli, J. W. Tobias, F. Rambow, P. Karras, J. C. Marine, X. Xu, A. G. Hatzigeorgiou, S. Ryeom, J. A. Diehl, S. Y. Fuchs, E. Pure, and C. Koumenis. A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nat Cell Biol. 2022. [doi] [url]

BibTeX

@article{RN48,
  author = {Verginadis, II and Avgousti, H. and Monslow, J. and Skoufos, G. and Chinga, F. and Kim, K. and Leli, N. M. and Karagounis, I. V. and Bell, B. I. and Velalopoulou, A. and Salinas, C. S. and Wu, V. S. and Li, Y. and Ye, J. and Scott, D. A. and Osterman, A. L. and Sengupta, A. and Weljie, A. and Huang, M. and Zhang, D. and Fan, Y. and Radaelli, E. and Tobias, J. W. and Rambow, F. and Karras, P. and Marine, J. C. and Xu, X. and Hatzigeorgiou, A. G. and Ryeom, S. and Diehl, J. A. and Fuchs, S. Y. and Pure, E. and Koumenis, C.},
  title = {A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression},
  journal = {Nat Cell Biol},
  volume = {24},
  number = {6},
  pages = {940-953},
  issn = {1476-4679 (Electronic)
  1465-7392 (Linking)},
  doi = {10.1038/s41556-022-00918-8},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/35654839},
  year = {2022},
  type = {Journal Article}
}

D. Pedri, P. Karras, E. Landeloos, J. C. Marine, and F. Rambow. Epithelial-to-mesenchymal-like transition events in melanoma. FEBS J. 2022. [doi] [url]

BibTeX

@article{RN55,
  author = {Pedri, D. and Karras, P. and Landeloos, E. and Marine, J. C. and Rambow, F.},
  title = {Epithelial-to-mesenchymal-like transition events in melanoma},
  journal = {FEBS J},
  volume = {289},
  number = {5},
  pages = {1352-1368},
  issn = {1742-4658 (Electronic)
  1742-464X (Linking)},
  doi = {10.1111/febs.16021},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/33999497},
  year = {2022},
  type = {Journal Article}
}

2021

I. Talon, A. Janiszewski, B. Theeuwes, T. Lefevre, J. Song, G. Bervoets, L. Vanheer, N. De Geest, S. Poovathingal, R. Allsop, J. C. Marine, F. Rambow, T. Voet, and V. Pasque. Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals. Genome Biol. 2021. [doi] [url]

BibTeX

@article{RN52,
  author = {Talon, I. and Janiszewski, A. and Theeuwes, B. and Lefevre, T. and Song, J. and Bervoets, G. and Vanheer, L. and De Geest, N. and Poovathingal, S. and Allsop, R. and Marine, J. C. and Rambow, F. and Voet, T. and Pasque, V.},
  title = {Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals},
  journal = {Genome Biol},
  volume = {22},
  number = {1},
  pages = {302},
  issn = {1474-760X (Electronic)
  1474-7596 (Linking)},
  doi = {10.1186/s13059-021-02518-5},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/34724962},
  year = {2021},
  type = {Journal Article}
}

F. Rapino, S. Delaunay, F. Rambow, Z. Zhou, L. Tharun, P. De Tullio, O. Sin, K. Shostak, S. Schmitz, J. Piepers, B. Ghesquiere, L. Karim, B. Charloteaux, D. Jamart, A. Florin, C. Lambert, A. Rorive, G. Jerusalem, E. Leucci, M. Dewaele, M. Vooijs, S. A. Leidel, M. Georges, M. Voz, B. Peers, R. Buttner, J. C. Marine, A. Chariot, and P. Close. Author Correction: Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2021. [doi] [url]

BibTeX

@article{RN51,
  author = {Rapino, F. and Delaunay, S. and Rambow, F. and Zhou, Z. and Tharun, L. and De Tullio, P. and Sin, O. and Shostak, K. and Schmitz, S. and Piepers, J. and Ghesquiere, B. and Karim, L. and Charloteaux, B. and Jamart, D. and Florin, A. and Lambert, C. and Rorive, A. and Jerusalem, G. and Leucci, E. and Dewaele, M. and Vooijs, M. and Leidel, S. A. and Georges, M. and Voz, M. and Peers, B. and Buttner, R. and Marine, J. C. and Chariot, A. and Close, P.},
  title = {Author Correction: Codon-specific translation reprogramming promotes resistance to targeted therapy},
  journal = {Nature},
  volume = {599},
  number = {7886},
  pages = {E14},
  issn = {1476-4687 (Electronic)
  0028-0836 (Linking)},
  doi = {10.1038/s41586-021-04074-1},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/34764478},
  year = {2021},
  type = {Journal Article}
}

A. Najem, J. Wouters, M. Krayem, F. Rambow, M. Sabbah, F. Sales, A. Awada, S. Aerts, F. Journe, J. C. Marine, and G. E. Ghanem. Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value. Front Oncol. 2021. [doi] [url]

BibTeX

@article{RN50,
  author = {Najem, A. and Wouters, J. and Krayem, M. and Rambow, F. and Sabbah, M. and Sales, F. and Awada, A. and Aerts, S. and Journe, F. and Marine, J. C. and Ghanem, G. E.},
  title = {Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value},
  journal = {Front Oncol},
  volume = {11},
  pages = {780654},
  issn = {2234-943X (Print)
  2234-943X (Linking)},
  doi = {10.3389/fonc.2021.780654},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/34869032},
  year = {2021},
  type = {Journal Article}
}

O. Marin-Bejar, A. Rogiers, M. Dewaele, J. Femel, P. Karras, J. Pozniak, G. Bervoets, N. Van Raemdonck, D. Pedri, T. Swings, J. Demeulemeester, S. V. Borght, S. Lehnert, F. Bosisio, J. J. van den Oord, I. V. Bempt, D. Lambrechts, T. Voet, O. Bechter, H. Rizos, M. P. Levesque, E. Leucci, A. W. Lund, F. Rambow, and J. C. Marine. Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma. Cancer Cell. 2021. [doi] [url]

BibTeX

@article{RN24,
  author = {Marin-Bejar, O. and Rogiers, A. and Dewaele, M. and Femel, J. and Karras, P. and Pozniak, J. and Bervoets, G. and Van Raemdonck, N. and Pedri, D. and Swings, T. and Demeulemeester, J. and Borght, S. V. and Lehnert, S. and Bosisio, F. and van den Oord, J. J. and Bempt, I. V. and Lambrechts, D. and Voet, T. and Bechter, O. and Rizos, H. and Levesque, M. P. and Leucci, E. and Lund, A. W. and Rambow, F. and Marine, J. C.},
  title = {Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma},
  journal = {Cancer Cell},
  volume = {39},
  number = {8},
  pages = {1135-1149 e8},
  issn = {1878-3686 (Electronic)
  1535-6108 (Linking)},
  doi = {10.1016/j.ccell.2021.05.015},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/34143978},
  year = {2021},
  type = {Journal Article}
}

M. Hamm, P. Sohier, V. Petit, J. H. Raymond, V. Delmas, M. Le Coz, F. Gesbert, C. Kenny, Z. Aktary, M. Pouteaux, F. Rambow, A. Sarasin, N. Charoenchon, A. Bellacosa, L. Sanchez-Del-Campo, L. Mosteo, M. Lauss, D. Meijer, E. Steingrimsson, G. B. Jonsson, R. A. Cornell, I. Davidson, C. R. Goding, and L. Larue. BRN2 is a non-canonical melanoma tumor-suppressor. Nat Commun. 2021. [doi] [url]

BibTeX

@article{RN18,
  author = {Hamm, M. and Sohier, P. and Petit, V. and Raymond, J. H. and Delmas, V. and Le Coz, M. and Gesbert, F. and Kenny, C. and Aktary, Z. and Pouteaux, M. and Rambow, F. and Sarasin, A. and Charoenchon, N. and Bellacosa, A. and Sanchez-Del-Campo, L. and Mosteo, L. and Lauss, M. and Meijer, D. and Steingrimsson, E. and Jonsson, G. B. and Cornell, R. A. and Davidson, I. and Goding, C. R. and Larue, L.},
  title = {BRN2 is a non-canonical melanoma tumor-suppressor},
  journal = {Nat Commun},
  volume = {12},
  number = {1},
  pages = {3707},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-021-23973-5},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/34140478},
  year = {2021},
  type = {Journal Article}
}

A. Gautron, L. Bachelot, M. Aubry, D. Leclerc, A. M. Quemener, S. Corre, F. Rambow, A. Paris, N. Tardif, H. M. Leclair, O. Marin-Bejar, C. Coulouarn, J. C. Marine, M. D. Galibert, and D. Gilot. CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and resistance. EMBO Mol Med. 2021. [doi] [url]

BibTeX

@article{RN16,
  author = {Gautron, A. and Bachelot, L. and Aubry, M. and Leclerc, D. and Quemener, A. M. and Corre, S. and Rambow, F. and Paris, A. and Tardif, N. and Leclair, H. M. and Marin-Bejar, O. and Coulouarn, C. and Marine, J. C. and Galibert, M. D. and Gilot, D.},
  title = {CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and resistance},
  journal = {EMBO Mol Med},
  volume = {13},
  number = {5},
  pages = {e13466},
  issn = {1757-4684 (Electronic)
  1757-4676 (Linking)},
  doi = {10.15252/emmm.202013466},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/33724679},
  year = {2021},
  type = {Journal Article}
}

C. Bosc, E. Saland, A. Bousard, N. Gadaud, M. Sabatier, G. Cognet, T. Farge, E. Boet, M. Gotanegre, N. Aroua, P. L. Mouchel, N. Polley, C. Larrue, E. Kaphan, M. Picard, A. Sahal, L. Jarrou, M. Tosolini, F. Rambow, F. Cabon, N. Nicot, L. Poillet-Perez, Y. Wang, X. Su, Q. Fovez, J. Kluza, R. J. Arguello, C. Mazzotti, H. Avet-Loiseau, F. Vergez, J. Tamburini, J. J. Fournie, I. S. Tiong, A. H. Wei, T. Kaoma, J. C. Marine, C. Recher, L. Stuani, C. Joffre, and J. E. Sarry. Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia. Nat Cancer. 2021. [doi] [url]

BibTeX

@article{RN49,
  author = {Bosc, C. and Saland, E. and Bousard, A. and Gadaud, N. and Sabatier, M. and Cognet, G. and Farge, T. and Boet, E. and Gotanegre, M. and Aroua, N. and Mouchel, P. L. and Polley, N. and Larrue, C. and Kaphan, E. and Picard, M. and Sahal, A. and Jarrou, L. and Tosolini, M. and Rambow, F. and Cabon, F. and Nicot, N. and Poillet-Perez, L. and Wang, Y. and Su, X. and Fovez, Q. and Kluza, J. and Arguello, R. J. and Mazzotti, C. and Avet-Loiseau, H. and Vergez, F. and Tamburini, J. and Fournie, J. J. and Tiong, I. S. and Wei, A. H. and Kaoma, T. and Marine, J. C. and Recher, C. and Stuani, L. and Joffre, C. and Sarry, J. E.},
  title = {Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia},
  journal = {Nat Cancer},
  volume = {2},
  number = {11},
  pages = {1204-1223},
  issn = {2662-1347 (Electronic)
  2662-1347 (Linking)},
  doi = {10.1038/s43018-021-00264-y},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/35122057},
  year = {2021},
  type = {Journal Article}
}

Z. Aktary, A. Conde-Perez, F. Rambow, M. Di Marco, F. Amblard, I. Hurbain, G. Raposo, C. Delevoye, S. Coscoy, and L. Larue. A role for Dynlt3 in melanosome movement, distribution, acidity and transfer. Commun Biol. 2021. [doi] [url]

BibTeX

@article{RN3,
  author = {Aktary, Z. and Conde-Perez, A. and Rambow, F. and Di Marco, M. and Amblard, F. and Hurbain, I. and Raposo, G. and Delevoye, C. and Coscoy, S. and Larue, L.},
  title = {A role for Dynlt3 in melanosome movement, distribution, acidity and transfer},
  journal = {Commun Biol},
  volume = {4},
  number = {1},
  pages = {423},
  issn = {2399-3642 (Electronic)
  2399-3642 (Linking)},
  doi = {10.1038/s42003-021-01917-5},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/33772156},
  year = {2021},
  type = {Journal Article}
}

2020

J. Wouters, Z. Kalender-Atak, L. Minnoye, K. I. Spanier, M. De Waegeneer, C. Bravo Gonzalez-Blas, D. Mauduit, K. Davie, G. Hulselmans, A. Najem, M. Dewaele, D. Pedri, F. Rambow, S. Makhzami, V. Christiaens, F. Ceyssens, G. Ghanem, J. C. Marine, S. Poovathingal, and S. Aerts. Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma. Nat Cell Biol. 2020. [doi] [url]

BibTeX

@article{RN47,
  author = {Wouters, J. and Kalender-Atak, Z. and Minnoye, L. and Spanier, K. I. and De Waegeneer, M. and Bravo Gonzalez-Blas, C. and Mauduit, D. and Davie, K. and Hulselmans, G. and Najem, A. and Dewaele, M. and Pedri, D. and Rambow, F. and Makhzami, S. and Christiaens, V. and Ceyssens, F. and Ghanem, G. and Marine, J. C. and Poovathingal, S. and Aerts, S.},
  title = {Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma},
  journal = {Nat Cell Biol},
  volume = {22},
  number = {8},
  pages = {986-998},
  issn = {1476-4679 (Electronic)
  1465-7392 (Linking)},
  doi = {10.1038/s41556-020-0547-3},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/32753671},
  year = {2020},
  type = {Journal Article}
}

N. Vandamme, G. Denecker, K. Bruneel, G. Blancke, O. Akay, J. Taminau, J. De Coninck, E. De Smedt, N. Skrypek, W. Van Loocke, J. Wouters, D. Nittner, C. Kohler, D. S. Darling, P. F. Cheng, M. I. G. Raaijmakers, M. P. Levesque, U. G. Mallya, M. Rafferty, B. Balint, W. M. Gallagher, L. Brochez, D. Huylebroeck, J. J. Haigh, V. Andries, F. Rambow, P. Van Vlierberghe, S. Goossens, J. J. van den Oord, J. C. Marine, and G. Berx. The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype. Cancer Res. 2020. [doi] [url]

BibTeX

@article{RN44,
  author = {Vandamme, N. and Denecker, G. and Bruneel, K. and Blancke, G. and Akay, O. and Taminau, J. and De Coninck, J. and De Smedt, E. and Skrypek, N. and Van Loocke, W. and Wouters, J. and Nittner, D. and Kohler, C. and Darling, D. S. and Cheng, P. F. and Raaijmakers, M. I. G. and Levesque, M. P. and Mallya, U. G. and Rafferty, M. and Balint, B. and Gallagher, W. M. and Brochez, L. and Huylebroeck, D. and Haigh, J. J. and Andries, V. and Rambow, F. and Van Vlierberghe, P. and Goossens, S. and van den Oord, J. J. and Marine, J. C. and Berx, G.},
  title = {The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype},
  journal = {Cancer Res},
  volume = {80},
  number = {14},
  pages = {2983-2995},
  issn = {1538-7445 (Electronic)
  0008-5472 (Linking)},
  doi = {10.1158/0008-5472.CAN-19-2373},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/32503808},
  year = {2020},
  type = {Journal Article}
}

K. Shostak, Z. Jiang, B. Charloteaux, A. Mayer, Y. Habraken, L. Tharun, S. Klein, X. Xu, H. Q. Duong, A. Vislovukh, P. Close, A. Florin, F. Rambow, J. C. Marine, R. Buttner, and A. Chariot. The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage. Nat Commun. 2020. [doi] [url]

BibTeX

@article{RN41,
  author = {Shostak, K. and Jiang, Z. and Charloteaux, B. and Mayer, A. and Habraken, Y. and Tharun, L. and Klein, S. and Xu, X. and Duong, H. Q. and Vislovukh, A. and Close, P. and Florin, A. and Rambow, F. and Marine, J. C. and Buttner, R. and Chariot, A.},
  title = {The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage},
  journal = {Nat Commun},
  volume = {11},
  number = {1},
  pages = {1270},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-020-15003-7},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/32152280},
  year = {2020},
  type = {Journal Article}
}

M. Scortegagna, K. Hockemeyer, I. Dolgalev, J. Pozniak, F. Rambow, Y. Li, Y. Feng, R. Tinoco, D. C. Otero, T. Zhang, K. Brown, M. Bosenberg, L. M. Bradley, J. C. Marine, I. Aifantis, and Z. A. Ronai. Siah2 control of T-regulatory cells limits anti-tumor immunity. Nat Commun. 2020. [doi] [url]

BibTeX

@article{RN40,
  author = {Scortegagna, M. and Hockemeyer, K. and Dolgalev, I. and Pozniak, J. and Rambow, F. and Li, Y. and Feng, Y. and Tinoco, R. and Otero, D. C. and Zhang, T. and Brown, K. and Bosenberg, M. and Bradley, L. M. and Marine, J. C. and Aifantis, I. and Ronai, Z. A.},
  title = {Siah2 control of T-regulatory cells limits anti-tumor immunity},
  journal = {Nat Commun},
  volume = {11},
  number = {1},
  pages = {99},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-019-13826-7},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/31911617},
  year = {2020},
  type = {Journal Article}
}

X. Li, P. Karras, R. Torres, F. Rambow, J. van den Oord, J. C. Marine, and L. Kos. Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. Cell Rep. 2020. [doi] [url]

BibTeX

@article{RN21,
  author = {Li, X. and Karras, P. and Torres, R. and Rambow, F. and van den Oord, J. and Marine, J. C. and Kos, L.},
  title = {Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites},
  journal = {Cell Rep},
  volume = {31},
  number = {11},
  pages = {107765},
  issn = {2211-1247 (Electronic)},
  doi = {10.1016/j.celrep.2020.107765},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/32553158},
  year = {2020},
  type = {Journal Article}
}

2019

A. Rogiers, D. Thomas, S. Vander Borght, J. J. van den Oord, O. Bechter, M. Dewaele, F. Rambow, J. C. Marine, and P. Wolter. Dabrafenib plus trametinib in BRAF K601E-mutant melanoma. Br J Dermatol. 2019. [doi] [url]

BibTeX

@article{RN39,
  author = {Rogiers, A. and Thomas, D. and Vander Borght, S. and van den Oord, J. J. and Bechter, O. and Dewaele, M. and Rambow, F. and Marine, J. C. and Wolter, P.},
  title = {Dabrafenib plus trametinib in BRAF K601E-mutant melanoma},
  journal = {Br J Dermatol},
  volume = {180},
  number = {2},
  pages = {421-422},
  issn = {1365-2133 (Electronic)
  0007-0963 (Linking)},
  doi = {10.1111/bjd.17250},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/30248172},
  year = {2019},
  type = {Journal Article}
}

F. Rambow, J. C. Marine, and C. R. Goding. Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities. Genes Dev. 2019. [doi] [url]

BibTeX

@article{RN34,
  author = {Rambow, F. and Marine, J. C. and Goding, C. R.},
  title = {Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities},
  journal = {Genes Dev},
  volume = {33},
  number = {19-20},
  pages = {1295-1318},
  issn = {1549-5477 (Electronic)
  0890-9369 (Linking)},
  doi = {10.1101/gad.329771.119},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/31575676},
  year = {2019},
  type = {Journal Article}
}

A. Janiszewski, I. Talon, J. Chappell, S. Collombet, J. Song, N. De Geest, S. K. To, G. Bervoets, O. Marin-Bejar, C. Provenzano, L. Vanheer, J. C. Marine, F. Rambow, and V. Pasque. Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming. Genome Res. 2019. [doi] [url]

BibTeX

@article{RN19,
  author = {Janiszewski, A. and Talon, I. and Chappell, J. and Collombet, S. and Song, J. and De Geest, N. and To, S. K. and Bervoets, G. and Marin-Bejar, O. and Provenzano, C. and Vanheer, L. and Marine, J. C. and Rambow, F. and Pasque, V.},
  title = {Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming},
  journal = {Genome Res},
  volume = {29},
  number = {10},
  pages = {1659-1672},
  issn = {1549-5469 (Electronic)
  1088-9051 (Linking)},
  doi = {10.1101/gr.249706.119},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/31515287},
  year = {2019},
  type = {Journal Article}
}

D. Garandeau, J. Noujarede, J. Leclerc, C. Imbert, V. Garcia, M. L. Bats, F. Rambow, J. Gilhodes, T. Filleron, N. Meyer, S. Brayer, S. Arcucci, S. Tartare-Deckert, B. Segui, J. C. Marine, T. Levade, C. Bertolotto, and N. Andrieu-Abadie. Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas. Mol Cancer Ther. 2019. [doi] [url]

BibTeX

@article{RN15,
  author = {Garandeau, D. and Noujarede, J. and Leclerc, J. and Imbert, C. and Garcia, V. and Bats, M. L. and Rambow, F. and Gilhodes, J. and Filleron, T. and Meyer, N. and Brayer, S. and Arcucci, S. and Tartare-Deckert, S. and Segui, B. and Marine, J. C. and Levade, T. and Bertolotto, C. and Andrieu-Abadie, N.},
  title = {Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas},
  journal = {Mol Cancer Ther},
  volume = {18},
  number = {2},
  pages = {289-300},
  issn = {1538-8514 (Electronic)
  1535-7163 (Linking)},
  doi = {10.1158/1535-7163.MCT-17-1141},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/30482853},
  year = {2019},
  type = {Journal Article}
}

C. C. Bell, K. A. Fennell, Y. C. Chan, F. Rambow, M. M. Yeung, D. Vassiliadis, L. Lara, P. Yeh, L. G. Martelotto, A. Rogiers, B. E. Kremer, O. Barbash, H. P. Mohammad, T. M. Johanson, M. L. Burr, A. Dhar, N. Karpinich, L. Tian, D. S. Tyler, L. MacPherson, J. Shi, N. Pinnawala, C. Yew Fong, A. T. Papenfuss, S. M. Grimmond, S. J. Dawson, R. S. Allan, R. G. Kruger, C. R. Vakoc, D. L. Goode, S. H. Naik, O. Gilan, E. Y. N. Lam, J. C. Marine, R. K. Prinjha, and M. A. Dawson. Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. Nat Commun. 2019. [doi] [url]

BibTeX

@article{RN4,
  author = {Bell, C. C. and Fennell, K. A. and Chan, Y. C. and Rambow, F. and Yeung, M. M. and Vassiliadis, D. and Lara, L. and Yeh, P. and Martelotto, L. G. and Rogiers, A. and Kremer, B. E. and Barbash, O. and Mohammad, H. P. and Johanson, T. M. and Burr, M. L. and Dhar, A. and Karpinich, N. and Tian, L. and Tyler, D. S. and MacPherson, L. and Shi, J. and Pinnawala, N. and Yew Fong, C. and Papenfuss, A. T. and Grimmond, S. M. and Dawson, S. J. and Allan, R. S. and Kruger, R. G. and Vakoc, C. R. and Goode, D. L. and Naik, S. H. and Gilan, O. and Lam, E. Y. N. and Marine, J. C. and Prinjha, R. K. and Dawson, M. A.},
  title = {Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia},
  journal = {Nat Commun},
  volume = {10},
  number = {1},
  pages = {2723},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-019-10652-9},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/31222014},
  year = {2019},
  type = {Journal Article}
}

C. Adriaens, F. Rambow, G. Bervoets, T. Silla, M. Mito, T. Chiba, H. Asahara, T. Hirose, S. Nakagawa, T. H. Jensen, and J. C. Marine. The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth. RNA. 2019. [doi] [url]

BibTeX

@article{RN1,
  author = {Adriaens, C. and Rambow, F. and Bervoets, G. and Silla, T. and Mito, M. and Chiba, T. and Asahara, H. and Hirose, T. and Nakagawa, S. and Jensen, T. H. and Marine, J. C.},
  title = {The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth},
  journal = {RNA},
  volume = {25},
  number = {12},
  pages = {1681-1695},
  issn = {1469-9001 (Electronic)
  1355-8382 (Linking)},
  doi = {10.1261/rna.071456.119},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/31551298},
  year = {2019},
  type = {Journal Article}
}

2018

A. Talebi, J. Dehairs, F. Rambow, A. Rogiers, D. Nittner, R. Derua, F. Vanderhoydonc, J. A. G. Duarte, F. Bosisio, K. Van den Eynde, K. Nys, M. V. Perez, P. Agostinis, E. Waelkens, J. Van den Oord, S. M. Fendt, J. C. Marine, and J. V. Swinnen. Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy. Nat Commun. 2018. [doi] [url]

BibTeX

@article{RN42,
  author = {Talebi, A. and Dehairs, J. and Rambow, F. and Rogiers, A. and Nittner, D. and Derua, R. and Vanderhoydonc, F. and Duarte, J. A. G. and Bosisio, F. and Van den Eynde, K. and Nys, K. and Perez, M. V. and Agostinis, P. and Waelkens, E. and Van den Oord, J. and Fendt, S. M. and Marine, J. C. and Swinnen, J. V.},
  title = {Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy},
  journal = {Nat Commun},
  volume = {9},
  number = {1},
  pages = {2500},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-018-04664-0},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/29950559},
  year = {2018},
  type = {Journal Article}
}

F. Rapino, S. Delaunay, F. Rambow, Z. Zhou, L. Tharun, P. De Tullio, O. Sin, K. Shostak, S. Schmitz, J. Piepers, B. Ghesquiere, L. Karim, B. Charloteaux, D. Jamart, A. Florin, C. Lambert, A. Rorive, G. Jerusalem, E. Leucci, M. Dewaele, M. Vooijs, S. A. Leidel, M. Georges, M. Voz, B. Peers, R. Buttner, J. C. Marine, A. Chariot, and P. Close. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018. [doi] [url]

BibTeX

@article{RN37,
  author = {Rapino, F. and Delaunay, S. and Rambow, F. and Zhou, Z. and Tharun, L. and De Tullio, P. and Sin, O. and Shostak, K. and Schmitz, S. and Piepers, J. and Ghesquiere, B. and Karim, L. and Charloteaux, B. and Jamart, D. and Florin, A. and Lambert, C. and Rorive, A. and Jerusalem, G. and Leucci, E. and Dewaele, M. and Vooijs, M. and Leidel, S. A. and Georges, M. and Voz, M. and Peers, B. and Buttner, R. and Marine, J. C. and Chariot, A. and Close, P.},
  title = {Codon-specific translation reprogramming promotes resistance to targeted therapy},
  journal = {Nature},
  volume = {558},
  number = {7711},
  pages = {605-609},
  issn = {1476-4687 (Electronic)
  0028-0836 (Linking)},
  doi = {10.1038/s41586-018-0243-7},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/29925953},
  year = {2018},
  type = {Journal Article}
}

F. Rambow, A. Rogiers, O. Marin-Bejar, S. Aibar, J. Femel, M. Dewaele, P. Karras, D. Brown, Y. H. Chang, M. Debiec-Rychter, C. Adriaens, E. Radaelli, P. Wolter, O. Bechter, R. Dummer, M. Levesque, A. Piris, D. T. Frederick, G. Boland, K. T. Flaherty, J. van den Oord, T. Voet, S. Aerts, A. W. Lund, and J. C. Marine. Toward Minimal Residual Disease-Directed Therapy in Melanoma. Cell. 2018. [doi] [url]

BibTeX

@article{RN36,
  author = {Rambow, F. and Rogiers, A. and Marin-Bejar, O. and Aibar, S. and Femel, J. and Dewaele, M. and Karras, P. and Brown, D. and Chang, Y. H. and Debiec-Rychter, M. and Adriaens, C. and Radaelli, E. and Wolter, P. and Bechter, O. and Dummer, R. and Levesque, M. and Piris, A. and Frederick, D. T. and Boland, G. and Flaherty, K. T. and van den Oord, J. and Voet, T. and Aerts, S. and Lund, A. W. and Marine, J. C.},
  title = {Toward Minimal Residual Disease-Directed Therapy in Melanoma},
  journal = {Cell},
  volume = {174},
  number = {4},
  pages = {843-855 e19},
  issn = {1097-4172 (Electronic)
  0092-8674 (Linking)},
  doi = {10.1016/j.cell.2018.06.025},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/30017245},
  year = {2018},
  type = {Journal Article}
}

H. Q. Duong, I. Nemazanyy, F. Rambow, S. C. Tang, S. Delaunay, L. Tharun, A. Florin, R. Buttner, D. Vandaele, P. Close, J. C. Marine, K. Shostak, and A. Chariot. The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids. Cancer Res. 2018. [doi] [url]

BibTeX

@article{RN12,
  author = {Duong, H. Q. and Nemazanyy, I. and Rambow, F. and Tang, S. C. and Delaunay, S. and Tharun, L. and Florin, A. and Buttner, R. and Vandaele, D. and Close, P. and Marine, J. C. and Shostak, K. and Chariot, A.},
  title = {The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids},
  journal = {Cancer Res},
  volume = {78},
  number = {16},
  pages = {4533-4548},
  issn = {1538-7445 (Electronic)
  0008-5472 (Linking)},
  doi = {10.1158/0008-5472.CAN-17-3149},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/29915160},
  year = {2018},
  type = {Journal Article}
}

S. Corre, N. Tardif, N. Mouchet, H. M. Leclair, L. Boussemart, A. Gautron, L. Bachelot, A. Perrot, A. Soshilov, A. Rogiers, F. Rambow, E. Dumontet, K. Tarte, A. Bessede, G. J. Guillemin, J. C. Marine, M. S. Denison, D. Gilot, and M. D. Galibert. Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma. Nat Commun. 2018. [doi] [url]

BibTeX

@article{RN8,
  author = {Corre, S. and Tardif, N. and Mouchet, N. and Leclair, H. M. and Boussemart, L. and Gautron, A. and Bachelot, L. and Perrot, A. and Soshilov, A. and Rogiers, A. and Rambow, F. and Dumontet, E. and Tarte, K. and Bessede, A. and Guillemin, G. J. and Marine, J. C. and Denison, M. S. and Gilot, D. and Galibert, M. D.},
  title = {Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma},
  journal = {Nat Commun},
  volume = {9},
  number = {1},
  pages = {4775},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/s41467-018-06951-2},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/30429474},
  year = {2018},
  type = {Journal Article}
}

2017

J. Peres, E. M. Kwesi-Maliepaard, F. Rambow, L. Larue, and S. Prince. The tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor. Cancer Lett. 2017. [doi] [url]

BibTeX

@article{RN28,
  author = {Peres, J. and Kwesi-Maliepaard, E. M. and Rambow, F. and Larue, L. and Prince, S.},
  title = {The tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor},
  journal = {Cancer Lett},
  volume = {405},
  pages = {111-119},
  issn = {1872-7980 (Electronic)
  0304-3835 (Linking)},
  doi = {10.1016/j.canlet.2017.07.018},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/28757416},
  year = {2017},
  type = {Journal Article}
}

M. Olvedy, J. C. Tisserand, F. Luciani, B. Boeckx, J. Wouters, S. Lopez, F. Rambow, S. Aibar, B. Thienpont, J. Barra, C. Kohler, E. Radaelli, S. Tartare-Deckert, S. Aerts, P. Dubreuil, J. J. van den Oord, D. Lambrechts, P. De Sepulveda, and J. C. Marine. Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma. J Clin Invest. 2017. [doi] [url]

BibTeX

@article{RN26,
  author = {Olvedy, M. and Tisserand, J. C. and Luciani, F. and Boeckx, B. and Wouters, J. and Lopez, S. and Rambow, F. and Aibar, S. and Thienpont, B. and Barra, J. and Kohler, C. and Radaelli, E. and Tartare-Deckert, S. and Aerts, S. and Dubreuil, P. and van den Oord, J. J. and Lambrechts, D. and De Sepulveda, P. and Marine, J. C.},
  title = {Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma},
  journal = {J Clin Invest},
  volume = {127},
  number = {6},
  pages = {2310-2325},
  issn = {1558-8238 (Electronic)
  0021-9738 (Linking)},
  doi = {10.1172/JCI91291},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/28463229},
  year = {2017},
  type = {Journal Article}
}

C. Kohler, D. Nittner, F. Rambow, E. Radaelli, F. Stanchi, N. Vandamme, A. Baggiolini, L. Sommer, G. Berx, J. J. van den Oord, H. Gerhardt, C. Blanpain, and J. C. Marine. Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes. Cell Stem Cell. 2017. [doi] [url]

BibTeX

@article{RN20,
  author = {Kohler, C. and Nittner, D. and Rambow, F. and Radaelli, E. and Stanchi, F. and Vandamme, N. and Baggiolini, A. and Sommer, L. and Berx, G. and van den Oord, J. J. and Gerhardt, H. and Blanpain, C. and Marine, J. C.},
  title = {Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes},
  journal = {Cell Stem Cell},
  volume = {21},
  number = {5},
  pages = {679-693 e6},
  issn = {1875-9777 (Electronic)
  1875-9777 (Linking)},
  doi = {10.1016/j.stem.2017.08.003},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/29033351},
  year = {2017},
  type = {Journal Article}
}

D. Gilot, M. Migault, L. Bachelot, F. Journe, A. Rogiers, E. Donnou-Fournet, A. Mogha, N. Mouchet, M. L. Pinel-Marie, B. Mari, T. Montier, S. Corre, A. Gautron, F. Rambow, P. El Hajj, R. Ben Jouira, S. Tartare-Deckert, J. C. Marine, B. Felden, G. Ghanem, and M. D. Galibert. A non-coding function of TYRP1 mRNA promotes melanoma growth. Nat Cell Biol. 2017. [doi] [url]

BibTeX

@article{RN17,
  author = {Gilot, D. and Migault, M. and Bachelot, L. and Journe, F. and Rogiers, A. and Donnou-Fournet, E. and Mogha, A. and Mouchet, N. and Pinel-Marie, M. L. and Mari, B. and Montier, T. and Corre, S. and Gautron, A. and Rambow, F. and El Hajj, P. and Ben Jouira, R. and Tartare-Deckert, S. and Marine, J. C. and Felden, B. and Ghanem, G. and Galibert, M. D.},
  title = {A non-coding function of TYRP1 mRNA promotes melanoma growth},
  journal = {Nat Cell Biol},
  volume = {19},
  number = {11},
  pages = {1348-1357},
  issn = {1476-4679 (Electronic)
  1465-7392 (Linking)},
  doi = {10.1038/ncb3623},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/28991221},
  year = {2017},
  type = {Journal Article}
}

S. Aibar, C. B. Gonzalez-Blas, T. Moerman, V. A. Huynh-Thu, H. Imrichova, G. Hulselmans, F. Rambow, J. C. Marine, P. Geurts, J. Aerts, J. van den Oord, Z. K. Atak, J. Wouters, and S. Aerts. SCENIC: single-cell regulatory network inference and clustering. Nat Methods. 2017. [doi] [url]

BibTeX

@article{RN2,
  author = {Aibar, S. and Gonzalez-Blas, C. B. and Moerman, T. and Huynh-Thu, V. A. and Imrichova, H. and Hulselmans, G. and Rambow, F. and Marine, J. C. and Geurts, P. and Aerts, J. and van den Oord, J. and Atak, Z. K. and Wouters, J. and Aerts, S.},
  title = {SCENIC: single-cell regulatory network inference and clustering},
  journal = {Nat Methods},
  volume = {14},
  number = {11},
  pages = {1083-1086},
  issn = {1548-7105 (Electronic)
  1548-7091 (Linking)},
  doi = {10.1038/nmeth.4463},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/28991892},
  year = {2017},
  type = {Journal Article}
}

2016

R. Riscal, E. Schrepfer, G. Arena, M. Y. Cisse, F. Bellvert, M. Heuillet, F. Rambow, E. Bonneil, F. Sabourdy, C. Vincent, I. Ait-Arsa, T. Levade, P. Thibaut, J. C. Marine, J. C. Portais, J. E. Sarry, L. Le Cam, and L. K. Linares. Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53. Mol Cell. 2016. [doi] [url]

BibTeX

@article{RN38,
  author = {Riscal, R. and Schrepfer, E. and Arena, G. and Cisse, M. Y. and Bellvert, F. and Heuillet, M. and Rambow, F. and Bonneil, E. and Sabourdy, F. and Vincent, C. and Ait-Arsa, I. and Levade, T. and Thibaut, P. and Marine, J. C. and Portais, J. C. and Sarry, J. E. and Le Cam, L. and Linares, L. K.},
  title = {Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53},
  journal = {Mol Cell},
  volume = {62},
  number = {6},
  pages = {890-902},
  issn = {1097-4164 (Electronic)
  1097-2765 (Linking)},
  doi = {10.1016/j.molcel.2016.04.033},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/27264869},
  year = {2016},
  type = {Journal Article}
}

F. Rambow, A. Bechadergue, F. Luciani, G. Gros, M. Domingues, J. Bonaventure, G. Meurice, J. C. Marine, and L. Larue. Regulation of Melanoma Progression through the TCF4/miR-125b/NEDD9 Cascade. J Invest Dermatol. 2016. [doi] [url]

BibTeX

@article{RN29,
  author = {Rambow, F. and Bechadergue, A. and Luciani, F. and Gros, G. and Domingues, M. and Bonaventure, J. and Meurice, G. and Marine, J. C. and Larue, L.},
  title = {Regulation of Melanoma Progression through the TCF4/miR-125b/NEDD9 Cascade},
  journal = {J Invest Dermatol},
  volume = {136},
  number = {6},
  pages = {1229-1237},
  issn = {1523-1747 (Electronic)
  0022-202X (Linking)},
  doi = {10.1016/j.jid.2016.02.803},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/26968260},
  year = {2016},
  type = {Journal Article}
}

M. Mrad, C. Imbert, V. Garcia, F. Rambow, N. Therville, S. Carpentier, B. Segui, T. Levade, R. Azar, J. C. Marine, M. Diab-Assaf, C. Colacios, and N. Andrieu-Abadie. Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma. Oncotarget. 2016. [doi] [url]

BibTeX

@article{RN25,
  author = {Mrad, M. and Imbert, C. and Garcia, V. and Rambow, F. and Therville, N. and Carpentier, S. and Segui, B. and Levade, T. and Azar, R. and Marine, J. C. and Diab-Assaf, M. and Colacios, C. and Andrieu-Abadie, N.},
  title = {Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma},
  journal = {Oncotarget},
  volume = {7},
  number = {44},
  pages = {71873-71886},
  issn = {1949-2553 (Electronic)
  1949-2553 (Linking)},
  doi = {10.18632/oncotarget.12380},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/27708249},
  year = {2016},
  type = {Journal Article}
}

M. Dewaele, T. Tabaglio, K. Willekens, M. Bezzi, S. X. Teo, D. H. Low, C. M. Koh, F. Rambow, M. Fiers, A. Rogiers, E. Radaelli, M. Al-Haddawi, S. Y. Tan, E. Hermans, F. Amant, H. Yan, M. Lakshmanan, R. C. Koumar, S. T. Lim, F. A. Derheimer, R. M. Campbell, Z. Bonday, V. Tergaonkar, M. Shackleton, C. Blattner, J. C. Marine, and E. Guccione. Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth. J Clin Invest. 2016. [doi] [url]

BibTeX

@article{RN10,
  author = {Dewaele, M. and Tabaglio, T. and Willekens, K. and Bezzi, M. and Teo, S. X. and Low, D. H. and Koh, C. M. and Rambow, F. and Fiers, M. and Rogiers, A. and Radaelli, E. and Al-Haddawi, M. and Tan, S. Y. and Hermans, E. and Amant, F. and Yan, H. and Lakshmanan, M. and Koumar, R. C. and Lim, S. T. and Derheimer, F. A. and Campbell, R. M. and Bonday, Z. and Tergaonkar, V. and Shackleton, M. and Blattner, C. and Marine, J. C. and Guccione, E.},
  title = {Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth},
  journal = {J Clin Invest},
  volume = {126},
  number = {1},
  pages = {68-84},
  issn = {1558-8238 (Electronic)
  0021-9738 (Linking)},
  doi = {10.1172/JCI82534},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/26595814},
  year = {2016},
  type = {Journal Article}
}

2015

A. Verfaillie, H. Imrichova, Z. K. Atak, M. Dewaele, F. Rambow, G. Hulselmans, V. Christiaens, D. Svetlichnyy, F. Luciani, L. Van den Mooter, S. Claerhout, M. Fiers, F. Journe, G. E. Ghanem, C. Herrmann, G. Halder, J. C. Marine, and S. Aerts. Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. Nat Commun. 2015. [doi] [url]

BibTeX

@article{RN46,
  author = {Verfaillie, A. and Imrichova, H. and Atak, Z. K. and Dewaele, M. and Rambow, F. and Hulselmans, G. and Christiaens, V. and Svetlichnyy, D. and Luciani, F. and Van den Mooter, L. and Claerhout, S. and Fiers, M. and Journe, F. and Ghanem, G. E. and Herrmann, C. and Halder, G. and Marine, J. C. and Aerts, S.},
  title = {Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state},
  journal = {Nat Commun},
  volume = {6},
  pages = {6683},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/ncomms7683},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/25865119},
  year = {2015},
  type = {Journal Article}
}

F. Rambow, B. Job, V. Petit, F. Gesbert, V. Delmas, H. Seberg, G. Meurice, E. Van Otterloo, P. Dessen, C. Robert, D. Gautheret, R. A. Cornell, A. Sarasin, and L. Larue. New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis. Cell Rep. 2015. [doi] [url]

BibTeX

@article{RN31,
  author = {Rambow, F. and Job, B. and Petit, V. and Gesbert, F. and Delmas, V. and Seberg, H. and Meurice, G. and Van Otterloo, E. and Dessen, P. and Robert, C. and Gautheret, D. and Cornell, R. A. and Sarasin, A. and Larue, L.},
  title = {New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis},
  journal = {Cell Rep},
  volume = {13},
  number = {4},
  pages = {840-853},
  issn = {2211-1247 (Electronic)},
  doi = {10.1016/j.celrep.2015.09.037},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/26489459},
  year = {2015},
  type = {Journal Article}
}

A. Conde-Perez, G. Gros, C. Longvert, M. Pedersen, V. Petit, Z. Aktary, A. Viros, F. Gesbert, V. Delmas, F. Rambow, B. C. Bastian, A. D. Campbell, S. Colombo, I. Puig, A. Bellacosa, O. Sansom, R. Marais, L. C. Van Kempen, and L. Larue. A caveolin-dependent and PI3K/AKT-independent role of PTEN in beta-catenin transcriptional activity. Nat Commun. 2015. [doi] [url]

BibTeX

@article{RN7,
  author = {Conde-Perez, A. and Gros, G. and Longvert, C. and Pedersen, M. and Petit, V. and Aktary, Z. and Viros, A. and Gesbert, F. and Delmas, V. and Rambow, F. and Bastian, B. C. and Campbell, A. D. and Colombo, S. and Puig, I. and Bellacosa, A. and Sansom, O. and Marais, R. and Van Kempen, L. C. and Larue, L.},
  title = {A caveolin-dependent and PI3K/AKT-independent role of PTEN in beta-catenin transcriptional activity},
  journal = {Nat Commun},
  volume = {6},
  pages = {8093},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/ncomms9093},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/26307673},
  year = {2015},
  type = {Journal Article}
}

2014

F. Rambow, A. Bechadergue, G. Saintigny, F. Morizot, C. Mahe, and L. Larue. miR-330-5p targets tyrosinase and induces depigmentation. J Invest Dermatol. 2014. [doi] [url]

BibTeX

@article{RN30,
  author = {Rambow, F. and Bechadergue, A. and Saintigny, G. and Morizot, F. and Mahe, C. and Larue, L.},
  title = {miR-330-5p targets tyrosinase and induces depigmentation},
  journal = {J Invest Dermatol},
  volume = {134},
  number = {11},
  pages = {2846-2849},
  issn = {1523-1747 (Electronic)
  0022-202X (Linking)},
  doi = {10.1038/jid.2014.231},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/24862846},
  year = {2014},
  type = {Journal Article}
}

M. J. Domingues, F. Rambow, B. Job, L. Papon, W. Liu, L. Larue, and J. Bonaventure. beta-catenin inhibitor ICAT modulates the invasive motility of melanoma cells. Cancer Res. 2014. [doi] [url]

BibTeX

@article{RN11,
  author = {Domingues, M. J. and Rambow, F. and Job, B. and Papon, L. and Liu, W. and Larue, L. and Bonaventure, J.},
  title = {beta-catenin inhibitor ICAT modulates the invasive motility of melanoma cells},
  journal = {Cancer Res},
  volume = {74},
  number = {7},
  pages = {1983-95},
  issn = {1538-7445 (Electronic)
  0008-5472 (Linking)},
  doi = {10.1158/0008-5472.CAN-13-0920},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/24514042},
  year = {2014},
  type = {Journal Article}
}

2013

S. J. Gallagher, F. Rambow, M. Kumasaka, D. Champeval, A. Bellacosa, V. Delmas, and L. Larue. Beta-catenin inhibits melanocyte migration but induces melanoma metastasis. Oncogene. 2013. [doi] [url]

BibTeX

@article{RN14,
  author = {Gallagher, S. J. and Rambow, F. and Kumasaka, M. and Champeval, D. and Bellacosa, A. and Delmas, V. and Larue, L.},
  title = {Beta-catenin inhibits melanocyte migration but induces melanoma metastasis},
  journal = {Oncogene},
  volume = {32},
  number = {17},
  pages = {2230-8},
  issn = {1476-5594 (Electronic)
  0950-9232 (Linking)},
  doi = {10.1038/onc.2012.229},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/22665063},
  year = {2013},
  type = {Journal Article}
}

2012

S. Makhzami, F. Rambow, V. Delmas, and L. Larue. Efficient gene expression profiling of laser-microdissected melanoma metastases. Pigment Cell Melanoma Res. 2012. [doi] [url]

BibTeX

@article{RN23,
  author = {Makhzami, S. and Rambow, F. and Delmas, V. and Larue, L.},
  title = {Efficient gene expression profiling of laser-microdissected melanoma metastases},
  journal = {Pigment Cell Melanoma Res},
  volume = {25},
  number = {6},
  pages = {783-91},
  issn = {1755-148X (Electronic)
  1755-1471 (Linking)},
  doi = {10.1111/pcmr.12013},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/22934821},
  year = {2012},
  type = {Journal Article}
}

S. Colombo, D. Champeval, F. Rambow, and L. Larue. Transcriptomic analysis of mouse embryonic skin cells reveals previously unreported genes expressed in melanoblasts. J Invest Dermatol. 2012. [doi] [url]

BibTeX

@article{RN6,
  author = {Colombo, S. and Champeval, D. and Rambow, F. and Larue, L.},
  title = {Transcriptomic analysis of mouse embryonic skin cells reveals previously unreported genes expressed in melanoblasts},
  journal = {J Invest Dermatol},
  volume = {132},
  number = {1},
  pages = {170-8},
  issn = {1523-1747 (Electronic)
  0022-202X (Linking)},
  doi = {10.1038/jid.2011.252},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/21850021},
  year = {2012},
  type = {Journal Article}
}

I. Berlin, F. Luciani, S. J. Gallagher, F. Rambow, A. Conde-Perez, S. Colombo, D. Champeval, V. Delmas, and L. Larue. General strategy to analyse coat colour phenotypes in mice. Pigment Cell Melanoma Res. 2012. [doi] [url]

BibTeX

@article{RN5,
  author = {Berlin, I. and Luciani, F. and Gallagher, S. J. and Rambow, F. and Conde-Perez, A. and Colombo, S. and Champeval, D. and Delmas, V. and Larue, L.},
  title = {General strategy to analyse coat colour phenotypes in mice},
  journal = {Pigment Cell Melanoma Res},
  volume = {25},
  number = {1},
  pages = {117-9},
  issn = {1755-148X (Electronic)
  1755-1471 (Linking)},
  doi = {10.1111/j.1755-148X.2011.00912.x},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/22085368},
  year = {2012},
  type = {Journal Article}
}

2011

C. R. Lindsay, S. Lawn, A. D. Campbell, W. J. Faller, F. Rambow, R. L. Mort, P. Timpson, A. Li, P. Cammareri, R. A. Ridgway, J. P. Morton, B. Doyle, S. Hegarty, M. Rafferty, I. G. Murphy, E. W. McDermott, K. Sheahan, K. Pedone, A. J. Finn, P. A. Groben, N. E. Thomas, H. Hao, C. Carson, J. C. Norman, L. M. Machesky, W. M. Gallagher, I. J. Jackson, L. Van Kempen, F. Beermann, C. Der, L. Larue, H. C. Welch, B. W. Ozanne, and O. J. Sansom. P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. Nat Commun. 2011. [doi] [url]

BibTeX

@article{RN22,
  author = {Lindsay, C. R. and Lawn, S. and Campbell, A. D. and Faller, W. J. and Rambow, F. and Mort, R. L. and Timpson, P. and Li, A. and Cammareri, P. and Ridgway, R. A. and Morton, J. P. and Doyle, B. and Hegarty, S. and Rafferty, M. and Murphy, I. G. and McDermott, E. W. and Sheahan, K. and Pedone, K. and Finn, A. J. and Groben, P. A. and Thomas, N. E. and Hao, H. and Carson, C. and Norman, J. C. and Machesky, L. M. and Gallagher, W. M. and Jackson, I. J. and Van Kempen, L. and Beermann, F. and Der, C. and Larue, L. and Welch, H. C. and Ozanne, B. W. and Sansom, O. J.},
  title = {P-Rex1 is required for efficient melanoblast migration and melanoma metastasis},
  journal = {Nat Commun},
  volume = {2},
  pages = {555},
  issn = {2041-1723 (Electronic)
  2041-1723 (Linking)},
  doi = {10.1038/ncomms1560},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/22109529},
  year = {2011},
  type = {Journal Article}
}

S. J. Gallagher, F. Luciani, I. Berlin, F. Rambow, G. Gros, D. Champeval, V. Delmas, and L. Larue. General strategy to analyse melanoma in mice. Pigment Cell Melanoma Res. 2011. [doi] [url]

BibTeX

@article{RN13,
  author = {Gallagher, S. J. and Luciani, F. and Berlin, I. and Rambow, F. and Gros, G. and Champeval, D. and Delmas, V. and Larue, L.},
  title = {General strategy to analyse melanoma in mice},
  journal = {Pigment Cell Melanoma Res},
  volume = {24},
  number = {5},
  pages = {987-8},
  issn = {1755-148X (Electronic)
  1755-1471 (Linking)},
  doi = {10.1111/j.1755-148X.2011.00907.x},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/21955491},
  year = {2011},
  type = {Journal Article}
}

S. Cortellino, J. Xu, M. Sannai, R. Moore, E. Caretti, A. Cigliano, M. Le Coz, K. Devarajan, A. Wessels, D. Soprano, L. K. Abramowitz, M. S. Bartolomei, F. Rambow, M. R. Bassi, T. Bruno, M. Fanciulli, C. Renner, A. J. Klein-Szanto, Y. Matsumoto, D. Kobi, I. Davidson, C. Alberti, L. Larue, and A. Bellacosa. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell. 2011. [doi] [url]

BibTeX

@article{RN9,
  author = {Cortellino, S. and Xu, J. and Sannai, M. and Moore, R. and Caretti, E. and Cigliano, A. and Le Coz, M. and Devarajan, K. and Wessels, A. and Soprano, D. and Abramowitz, L. K. and Bartolomei, M. S. and Rambow, F. and Bassi, M. R. and Bruno, T. and Fanciulli, M. and Renner, C. and Klein-Szanto, A. J. and Matsumoto, Y. and Kobi, D. and Davidson, I. and Alberti, C. and Larue, L. and Bellacosa, A.},
  title = {Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair},
  journal = {Cell},
  volume = {146},
  number = {1},
  pages = {67-79},
  issn = {1097-4172 (Electronic)
  0092-8674 (Linking)},
  doi = {10.1016/j.cell.2011.06.020},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/21722948},
  year = {2011},
  type = {Journal Article}
}

2010

F. Rambow and L. Larue. The quest for the melanoma stem cell: still more questions than answers. Pigment Cell Melanoma Res. 2010. [doi] [url]

BibTeX

@article{RN32,
  author = {Rambow, F. and Larue, L.},
  title = {The quest for the melanoma stem cell: still more questions than answers},
  journal = {Pigment Cell Melanoma Res},
  volume = {23},
  number = {3},
  pages = {307-9},
  issn = {1755-148X (Electronic)
  1755-1471 (Linking)},
  doi = {10.1111/j.1755-148X.2010.00713.x},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/20444202},
  year = {2010},
  type = {Journal Article}
}

2008

F. Rambow, G. Piton, S. Bouet, J. J. Leplat, S. Baulande, A. Marrau, M. Stam, V. Horak, and S. Vincent-Naulleau. Gene expression signature for spontaneous cancer regression in melanoma pigs. Neoplasia. 2008. [doi] [url]

BibTeX

@article{RN35,
  author = {Rambow, F. and Piton, G. and Bouet, S. and Leplat, J. J. and Baulande, S. and Marrau, A. and Stam, M. and Horak, V. and Vincent-Naulleau, S.},
  title = {Gene expression signature for spontaneous cancer regression in melanoma pigs},
  journal = {Neoplasia},
  volume = {10},
  number = {7},
  pages = {714-26, 1 p following 726},
  issn = {1476-5586 (Electronic)
  1476-5586 (Linking)},
  doi = {10.1593/neo.08344},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/18592010},
  year = {2008},
  type = {Journal Article}
}

F. Rambow, O. Malek, C. Geffrotin, J. J. Leplat, S. Bouet, G. Piton, K. Hugot, C. Bevilacqua, V. Horak, and S. Vincent-Naulleau. Identification of differentially expressed genes in spontaneously regressing melanoma using the MeLiM swine model. Pigment Cell Melanoma Res. 2008. [doi] [url]

BibTeX

@article{RN33,
  author = {Rambow, F. and Malek, O. and Geffrotin, C. and Leplat, J. J. and Bouet, S. and Piton, G. and Hugot, K. and Bevilacqua, C. and Horak, V. and Vincent-Naulleau, S.},
  title = {Identification of differentially expressed genes in spontaneously regressing melanoma using the MeLiM swine model},
  journal = {Pigment Cell Melanoma Res},
  volume = {21},
  number = {2},
  pages = {147-61},
  issn = {1755-1471 (Print)
  1755-1471 (Linking)},
  doi = {10.1111/j.1755-148X.2008.00442.x},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/18426408},
  year = {2008},
  type = {Journal Article}
}

2007

F. W. Velten, F. Rambow, P. Metharom, and S. Goerdt. Enhanced T-cell activation and T-cell-dependent IL-2 production by CD83+, CD25high, CD43high human monocyte-derived dendritic cells. Mol Immunol. 2007. [doi] [url]

BibTeX

@article{RN45,
  author = {Velten, F. W. and Rambow, F. and Metharom, P. and Goerdt, S.},
  title = {Enhanced T-cell activation and T-cell-dependent IL-2 production by CD83+, CD25high, CD43high human monocyte-derived dendritic cells},
  journal = {Mol Immunol},
  volume = {44},
  number = {7},
  pages = {1544-50},
  issn = {0161-5890 (Print)
  0161-5890 (Linking)},
  doi = {10.1016/j.molimm.2006.08.020},
  url = {https://www.ncbi.nlm.nih.gov/pubmed/17023048},
  year = {2007},
  type = {Journal Article}
}